Zampatti was placed “under observation” at Sydney’s St Vincent’s Hospital after falling down stairs at the opening of La Traviata at Mrs Macquarie’s Point last Friday Night.

It’s understood she was in a coma and never woke up, The Daily Telegraphreports.

She was rendered unconscious from the fall and was assisted by a first aid professional, before ambulance officers treated her at the scene and she was transported to hospital.

“Carla is very grateful for the support from medically trained members of the audience who assisted and for the excellent care from the team at St Vincent’s Hospital,” a family spokesman said earlier this week.

Legendary Australian fashion designer Carla Zampatti has died at the age of 78, following a week-long hospitalisation after a fall at the Opera last weekend. Picture: Dan Arnold/WireImageSource:Getty Images

Zampatti was taken by ambulance to Sydney’s St Vincent’s Hospital after the fall last Friday night. Picture: SuppliedSource:Supplied

The industry pioneer, born in Italy and settling in Australia with her family in 1950, has enjoyed a career spanning nearly six decades, with big names celebrities at home and abroad dedicated fans of her eponymous label.

“Carla Zampatti is Australia’s most successful and enduring fashion designer, launching her eponymous label in 1965,” a statement, released after her death this morning, read.

“Executive Chairman of Carla Zampatti Pty Ltd, Carla has long been celebrated for making Australian women feel confident and elegant through her exceptional design, tailoring and understanding of the modern world.

A tribute to Zampatti from her daughter Bianca Spender. Picture: InstagramSource:Instagram

Zampatti, pictured in 1995, produced her first small fashion collection in 1965. Picture: SuppliedSource:News Limited

With her second husband, John Spender, in September 1984.Source:News Corp Australia

“Born in Italy, Carla settled with her family in Western Australia in 1950. After moving to Sydney in her 20s, she produced her first small fashion collection in 1965. Two years later she launched her collection nationally and in 1970 established Carla Zampatti Pty Ltd.

“A champion of Australian women and a multicultural success story, she continued to thrive as a businesswoman through enormous radical and social change, designing clothes for women fighting for liberation through the women’s rights movement in the 1960s to empowering women today in leadership, the workplace, in their home and at major life events.

“She went on to expand her retail network to create a chain of boutiques across Australia and New Zealand and her clothes are truly considered a distinctive part of modern Australian lifestyle. Her designs have been worn by Australia’s most influential women from Prime Ministers and Premiers to business leaders, dignitaries, award-winning journalists, royalty and celebrities. They include Princess Mary of Denmark, Dame Quentin Bryce, Julia Gillard, Gladys Berejiklian, Julie Bishop, Nicole Kidman and Cate Blanchett.”

The mother-of-three and “proud Nonna”, pictured in April 2014. Picture: Ryan Pierse/Getty ImagesSource:Getty Images

With one of her two daughters, designer Bianca Spender.Source:Supplied

In 1987, Zampatti was awarded a Member of the Order of Australia, and, in 2009, a Companion of the Order of Australia. She was appointed Commander in the Order of Merit of the Italian Republic in 2004 by the Italian government, and awarded the Australian Fashion Laureate award for lifetime achievement four years later.

Zampatti had three children – son Alexander Schuman, with her first husband Leo Schuman – and two daughters, Bianca Spender and Allegra Spender, from her marriage to former Australian lawyer, politician and diplomat, John Spender.

She was also the “proud Nonna” of nine grandchildren.

“Her family is very grateful for the support and for the excellent care from the team at St Vincent’s Hospital Sydney,” the statement said.

“A condolence page has been established at Carla Zampatti AC|Farewelling memorial. The family ask for privacy at this time.”